Anti-diabetic drugs are medications used to treat diabetes, a condition in which the body has difficulty regulating blood sugar levels. While these drugs can be effective in managing diabetes, they can also have side effects. The specific side effects depend on the type of drug and individual factors, such as age, overall health, and other medications taken.

Here are some common side effects associated with different types of anti-diabetic drugs:

1. Metformin: This is a commonly used drug for type 2 diabetes. Its side effects may include nausea, vomiting, diarrhea, abdominal pain, and a metallic taste in the mouth. Rarely, it can cause lactic acidosis, a serious condition that can be life-threatening.

2. Sulfonylureas: These drugs stimulate the pancreas to release more insulin. Their side effects may include low blood sugar (hypoglycemia), weight gain, upset stomach, and skin rash.

3. Meglitinides: These drugs work similarly to sulfonylureas but have a shorter duration of action. Their side effects may include low blood sugar, weight gain, and headache.

4. Thiazolidinediones (TZDs): These drugs help the body use insulin more effectively. Their side effects may include fluid retention, weight gain, and an increased risk of fractures.

5. DPP-4 inhibitors: These drugs increase insulin production and decrease the production of glucose. Their side effects may include headache, upper respiratory tract infections, and pancreatitis.

6. GLP-1 receptor agonists: These drugs stimulate insulin secretion and slow down digestion. Their side effects may include nausea, vomiting, diarrhea, and pancreatitis.

It is important to note that the benefits of anti-diabetic drugs often outweigh their side effects. However, it is important to discuss any concerns with a healthcare provider and report any side effects experienced.